Four children and their parents were killed in a hand-grenade blast in Pakistan's restive northwest on Sunday, a day after 12 children were killed by a bomb hidden in a football. The grenade exploded in a car carrying a couple and their eight children near Datta Kheil, a district in the North Waziristan tribal region, near the Afghan border. "The parents and four of their children died instantly and their bodies were brought to hospital," Mirbad Khan, a hospital official in Miranshah, the main town of North Waziristan, said. "Four other children were wounded," according to a report of Reuters.