Twenty-one people in the Istanbul area are in hospital amid fears they have bird flu, newspapers said on Monday, raising concern the deadly disease has spread to Turkey's commercial hub of 12 million people. Health authorities expect to receive test results on the 21 people on Monday, the Milliyet daily said. Istanbul province deputy health director Mehmet Bakar said initial tests on two dead chickens in the Istanbul district of Kucukcekmece indicated they were infected by the bird flu virus, the reports said. A third test was being carried out to determine the definitive diagnosis. "21 people under suspicion (of having bird flu) have been kept in hospital under observation. Samples have been taken from these people and sent to the laboratory for examination," Bakar was quoted as saying in Star newspaper.