US President Barack Obama and Cuban President Raul Castro arrived in Panama for the Friday start of the Summit of the Americas, where the two are set to meet officially for the first time since declaring a thaw in bilateral relations that had been frozen for more than 50 years, dpa reported. The two-day summit brings together leaders and delegates of 35 countries in the Americas, but all eyes were on the two former archenemies on the cusp of historic change. The White House said before the summit that while no formal bilateral meeting was yet scheduled between Obama and Castro, they were expected to "interact" at the summit, at official meetings and on the sidelines. "There are many opportunities for leaders to have conversations," White House advisor Ben Rhodes said in a media briefing.