More than 20,000 international HIV researchers and activists will gather in Washington later this month with a sense of optimism not seen in many years—that that it finally may be possible to prevent the spread of the AIDS virus, researchers said Saturday. “We want to make sure we do not overpromise," Dr. Anthony Fauci, the National Institutes of Health's infectious disease chief, told The Associated Press. But, he said, “I think we are at a turning point." The big new focus is on trying to get more people with HIV treated early, when they are first infected, instead of waiting until they are weakened or sick, as the world largely has done until now. Staying healthier also makes them less likely to infect others. Studies over the past two years have shown what Fauci calls “striking, sometimes breathtaking results," in preventing people at high risk of HIV from getting it in some of the hardest-hit countries, using this treatment-as-prevention and some other protections. Now, as the International AIDS Conference returns to the United States for the first time in 22 years, the question is whether the world will come up with the money and the know-how to put the best combinations of protections into practice, for AIDS-ravaged poor countries and hot spots in developed nations as well. “We have the tools to make it happen," said Dr. Elly Katabira, the president of the International AIDS Society, which organizes the world's largest HIV conference, set for July 22-27. He points to strides already in Botswana and Rwanda in increasing access to AIDS drugs. But Fauci cautioned that moving those tools into everyday life is “a daunting challenge," given the costs of medications and the difficulty in getting people to take them for years despite poverty and other competing health and social problems.