U.S. Secretary of State Hillary Clinton and Mexican Foreign Minister Patricia Espinosa led talks between their two countries aimed at fighting drug cartels and improving broader cooperation in several areas. Posing for photographers in Washington, Clinton thanked Espinosa and her government "for the very important work we are doing together between our two countries and also for Mexico's leadership on so many regional and global issues." The top diplomats headed delegations that included the heads of defense, security, law enforcement, immigration, and border agencies. "We will review our cooperation in many areas, and particularly the areas of security," Espinosa said, adding that Presidents Felipe Calderon and Barack Obama have "given clear instructions" to both sides to cooperate. "This is the only way that we will be able to face the challenges in this area." Attending the talks were U.S. Defense Secretary Robert Gates and his Mexican counterpart Guillermo Galvan, U.S. Homeland Security Secretary Janet Napolitano and Mexican Interior Minister Francisco Blake, and U.S. Attorney General Eric Holder and his counterpart Marisela Morales.