A deep-sea expedition by the United States and Indonesia sets off this week to explore one of the world's last frontiers, an adventure that researchers hope could lead to cures for diseases and help in predicting deadly tsunamis. Scientists portray the trip to Indonesian waters as a throwback to a time when explorers blazed new trails into unknown territory, AP reported. The expedition, which is set to begin Thursday and wrap up in early August, is the maiden voyage for a high-tech U.S. science ship and the first joint deep-sea exploration by Indonesia and the United States. Scientists will use a powerful sonar mapping system and a robotic vehicle equipped with high-definition video cameras to explore hundreds of square miles (kilometers) north of the Indonesian archipelago, providing an extraordinary glimpse of one of the globe's most diverse, complex and little-known marine ecosystems.