In his final radio address, President Bush reminded the nation Saturday that it still faces a serious threat from enemies that he warned are patient and determined to strike again. The president urged Americans not to become complacent just because the attacks of Sept. 11, 2001, are fading from memory. "We must keep our resolve, and we must never let down our guard," he said. At the same time, Bush said the U.S. must not isolate itself or retreat from engagement with the rest of the world. "Retreating behind our borders would only invite danger," he said. "In the 21st century, security and prosperity at home depend on the expansion of liberty abroad. If America does not lead the cause of freedom, that cause will not be led." His radio address was similar to the farewell address he gave to the nation on Thursday night in which he called the inauguration of Barack Obama, who becomes the first black president, a "moment of hope and pride" for America. Bush said he and first lady Laura Bush offer their best wishes to Obama, his wife, Michelle, and their two young daughters.