lowering drug Vytorin did not lower the risk of heart-valve problems or the need for surgery. Its shares fell 6 percent. The broader Standard & Poor's 500 index was little changed, falling 0.68 to 1,260.00. The technology-heavy Nasdaq composite index fell 3.25, or 0.1 percent, to 2,279.53. Yahoo announced a settlement with investor Carl Icahn over its candidates for board of directors. Its shares fell 3 percent. The New York Stock Exchange composite index rose 45.89 to 8,499.74. The American Stock Exchange composite index rose 7.68 to 2,155.31. And the Russell 2000 index rose 4.55 to 697.63.