French and Spanish police captured the political leader of the militant Basque separatist group ETA overnight, Spanish Interior Minister Alfredo Perez Rubalcaba confirmed Wednesday, saying the arrest was a major success for Spain's anti-terrorist campaign, according to dpa. Francisco Javier Lopez Pena alias Thierry, 49, was held with three other ETA suspects in a flat in the south-western French city of Bordeaux. A French citizen linked with the flat was also arrested. Spanish police later detained a sixth person, a former Basque mayor, on charges of having met several times with the four ETA suspects. The arrest of Lopez Pena "is not just another operation," Rubalcaba said in the Senegalese capital Dakar. He described Lopez Pena as being probably "the person with the most political and military weight" within ETA. The minister interrupted his African tour to return to Madrid. Police broke into the Bordeaux flat when the ETA suspects were holding a meeting, reportedly to plan attacks. The four carried pistols, but did not resist arrest. They covered their heads and shouted pro-ETA slogans on being taken to police vehicles. Police seized munition, a small quantity of explosives as well as abundant documents and computer materials. The suspects were taken back to the flat Wednesday for a more thorough house search. Meanwhile in Spain, Jose Antonio Barandiaran Ezama was held in the Basque town of Andoain, where he was mayor from 1999 to 2003 for the Basque separatist party Euskal Herritarrok (EH), currently banned under the name of Batasuna. Barandiaran's home was searched. Spanish prosecutors requested the extradition of Lopez Pena and the three others from France. The arrest of ETA hardliner Lopez Pena, who had been on the run from police for 25 years, was regarded as the heaviest blow to the group in years. Lopez Pena is held partly responsible for the failure of Prime Minister Jose Luis Rodriguez Zapatero's attempt at a peace process with ETA in 2006, and is believed to have ordered the group's main attacks since then. Lopez Pena is believed to have joined ETA in 1980. After serving a prison sentence for extortion, he became responsible for ETA's arms caches, trained terrorists, and rose to become one of ETA's top leaders in recent years. In the summer of 2006, the Zapatero government announced a peace process with ETA in an attempt to end the group's armed campaign that has cost more than 820 lives over four decades. Towards the end of the process, Lopez Pena replaced another ETA leader, Josu Ternera, in meetings with the government, tabling tough demands on Basque self-determination that the government had not expected, according to media reports. Lopez Pena then allegedly ordered a car bombing that killed two Ecuadorian immigrants in a Madrid airport underground parking lot in December 2006. The attempt to pressure the government caused the peace process to definitively collapse. Lopez Pena ordered an official end to ETA's 14-month ceasefire in June 2007, and launched a violent campaign to make the government "pay" for the failure of the peace process. Attacks believed to have been ordered by Lopez Pena included the killing of former Socialist councillor Isaias Carrasco two days before the March 9 general elections, and a car bombing that killed police officer Juan Manuel Pinuel a week ago. Lopez Pena was the third party in ETA's current leadership, which also includes two military leaders, according to the daily El Pais. In addition to living in France, where ETA has long had a large part of its infrastructure, Lopez Pena has spent time in Cuba to stay out of the reach of Spanish police. The suspects who were captured with him were Ainhoa Ozaeta Mendiondo, who was Barandiaran's deputy mayor and announced the beginning of the ceasefire in March 2006; Igor Suberbiola, suspected of planning attacks against Spain's tourism branch, and Jon Salaberria. Salaberria is a former member of the Basque regional parliament for Batasuna, the political wing of ETA which was outlawed in 2003. He is suspected of helping to finance ETA through a network of separatist bars in the Basque region. The arrests followed a months-long joint French-Spanish investigation, which gathered speed after the car bombing that killed Pinuel in the Basque town of Legutiano. The French government welcomed the arrests, with Interior Minister Michele Alliot-Marie praising the "good cooperation of the Spanish and French security forces." The Spanish government has cracked down on ETA since the end of the peace process. Dozens of suspected ETA members or collaborators have been detained. ETA leaders have been captured in some half a dozen police swoops since 1986. The arrest of Lopez Pena was regarded as the most important one since that of political leader Mikel Albisu in south- western France in 2004. In its most recent attack on Monday, ETA bombed a nautical club in the Basque town of Getxo, causing serious material damage but no injuries. On Tuesday, Zapatero rejected a request by the Basque regional government for a regional referendum on self-determination. Regional Prime Minister Juan Jose Ibarretxe believes the vote would help to solve the problem of ETA.