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Vitamin D helps kidney patients live longer -study
Published in Saudi Press Agency on 07 - 05 - 2008


Kidney disease patients who took
a prescription form of Vitamin D were 26 percent less likely to
die over a two-year span than those not taking the vitamin,
U.S. researchers said on Wednesday, according to Reuters.
Vitamin D helps the body absorb calcium and is important
for bone health, but several recent studies suggest that this
vitamin may have other benefits, such as protecting against
heart disease.
Dr. Bryan Kestenbaum of the University of Washington in
Seattle conducted a two-year study to see what impact the drug
would have on improving the health of kidney disease patients
with severely reduced renal function.
People with advanced kidney disease often take a form of
Vitamin D to bring down high levels of a hormone secreted by
the parathyroid glands in the neck that controls calcium
metabolism. Too much of the hormone can weaken bones.
Kestenbaum's team studied 1,418 patients who had moderate
to severe chronic kidney disease. All patients also had high
parathyroid hormone levels, which is often caused by kidney
failure.
One group was being treated with the drug calcitriol, a
synthetic form of Vitamin D, to lower their parathyroid hormone
levels. Another group was not taking the drug.
After two years, the researchers compared death rates,
adjusting for differences in age, kidney function, parathyroid
hormone levels and other illnesses.
They found patients taking the drug had a 26 percent lower
risk of death compared to people not taking the drug. They also
were less likely to develop end-stage kidney disease.
"Recently, there has been an increased focus on the effects
of vitamin D beyond those on bone health," Kestenbaum, whose
study appears in the Journal of the American Society of
Nephrology, said in a statement.
Other studies have found that people undergoing kidney
dialysis who are treated with an intravenous form of Vitamin D
lived longer than those who are not treated with the drug.
Kestenbaum said more study is needed to see if the use of
prescription forms of Vitamin D might reduce the risk of heart
disease. He also thinks researchers should test cheaper,
non-prescription versions of the vitamin.
In adults, vitamin D deficiency can lead to osteoporosis,
and it can lead to rickets in children.
The body makes vitamin D when skin is exposed to sunlight.
It is found in fatty fish such as salmon and milk commonly is
fortified with it.


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