Roche Holding AG said Tuesday it will acquire U.S.-based medical diagnostic product maker Ventana Medical Systems Inc. for US$3.4 billion (¤2.36 billion). The deal was reached after Roche raised its offer per share by about 19 percent to US$89.50 (¤62.08) from US$75 (¤52.02) per share, the Swiss pharmaceuticals company said. Ventana's board of directors, which had previously rejected Roche's advances, will recommend that shareholders accept the offer, according to a joint statement by the two companies quoted by the Associated Press.