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Scientist find fat gene, but no clue yet how it works
Published in Saudi Press Agency on 12 - 04 - 2007


British researchers have discovered that
people who carry two copies of a gene named FTO weighed on
average 7 pounds (3.28 kilograms) more than people who lack
it.
Unlike other genes thought to be involved with appetite or
calorie burning, scientists have no idea yet what FTO is
supposed to do, according to AP.
But research published in Friday's edition of the journal
Science shows strong evidence of a link. Using blood
samples provided by more than 38,000 people, scientists
found that those who had one copy of the gene variation had
a 30 percent increased risk of obesity, and carriers of two
copies had almost a 70 percent increased risk.
The study included mostly white Europeans, and about one
in six of them are thought to carry two copies of the gene
variant, concluded the British team, from the University of
Oxford and the Peninsula Medical Center in Exeter.
Obeisity is becoming a problem in many European countries,
and millions are overweight. Bad diets and too little
exercise are the chief factors. But innate biology plays
some role, and researchers are exploring a variety of genes
and hormones that seem involved in the balancing act of
weight gain and loss.
The work was funded by the Wellcome Trust, a British
medical charity.
-- SPA


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