Literature Commission inaugurates Saudi Pavilion at Muscat Book Fair    Saudi Minister of Culture holds talks with his Costa Rican counterpart in Jeddah    Saudi Arabia cracks down on fraudulent Hajj campaigns, urges pilgrims to use official channels    Nammos Amala Resort to open soon with Saudi-Greek designs    Saudi Arabia completes 674 Vision 2030 initiatives, achieves 93% of KPIs as ninth-year milestone marked    MHRSD: 80% of recruitment offices are non-compliant with regulations    GACA chief chairs 16th meeting of the Steering Committee on aviation's strategy    Alkhorayef praises advancements in Al-Kharj food industries sector    At least 50 Palestinians killed in Israeli strikes across Gaza    Teenage girl killed in French school stabbing attack    Trump claims meeting with China after Beijing denies any trade negotiations    Police fatally shoot man at Toronto's international airport    Saudi Theater Commission launches its Work and Learn Project in UK    The season has begun — and one comment shook us all    Jennifer Lopez dazzles in Jeddah with a Formula 1 performance    Saudi Arabia open to expanded 64-team World Cup in 2034, says sports minister    Average life expectancy in Saudi Arabia rises to78.8 years    Super Max Verstappen scorches to pole with record lap in Jeddah    Film Commission launches 'Cinema' initiative to enhance content    Famed Philippine film star Nora Aunor dies at 71    Pakistani star's Bollywood return excites fans and riles far right    Veteran Bollywood actor Manoj Kumar dies at 87    Bollywood actress vindicated over boyfriend's death after media hounding    Grand Mufti rules against posting prayers and preaching in mosques on social media    Exotic Taif Roses Simulation Performed at Taif Rose Festival    Asian shares mixed Tuesday    Weather Forecast for Tuesday    Saudi Tourism Authority Participates in Arabian Travel Market Exhibition in Dubai    Minister of Industry Announces 50 Investment Opportunities Worth over SAR 96 Billion in Machinery, Equipment Sector    HRH Crown Prince Offers Condolences to Crown Prince of Kuwait on Death of Sheikh Fawaz Salman Abdullah Al-Ali Al-Malek Al-Sabah    HRH Crown Prince Congratulates Santiago Peña on Winning Presidential Election in Paraguay    SDAIA Launches 1st Phase of 'Elevate Program' to Train 1,000 Women on Data, AI    41 Saudi Citizens and 171 Others from Brotherly and Friendly Countries Arrive in Saudi Arabia from Sudan    Saudi Arabia Hosts 1st Meeting of Arab Authorities Controlling Medicines    General Directorate of Narcotics Control Foils Attempt to Smuggle over 5 Million Amphetamine Pills    NAVI Javelins Crowned as Champions of Women's Counter-Strike: Global Offensive (CS:GO) Competitions    Saudi Karate Team Wins Four Medals in World Youth League Championship    Third Edition of FIFA Forward Program Kicks off in Riyadh    Evacuated from Sudan, 187 Nationals from Several Countries Arrive in Jeddah    SPA Documents Thajjud Prayer at Prophet's Mosque in Madinah    SFDA Recommends to Test Blood Sugar at Home Two or Three Hours after Meals    SFDA Offers Various Recommendations for Safe Food Frying    SFDA Provides Five Tips for Using Home Blood Pressure Monitor    SFDA: Instant Soup Contains Large Amounts of Salt    Mawani: New shipping service to connect Jubail Commercial Port to 11 global ports    Custodian of the Two Holy Mosques Delivers Speech to Pilgrims, Citizens, Residents and Muslims around the World    Sheikh Al-Issa in Arafah's Sermon: Allaah Blessed You by Making It Easy for You to Carry out This Obligation. Thus, Ensure Following the Guidance of Your Prophet    Custodian of the Two Holy Mosques addresses citizens and all Muslims on the occasion of the Holy month of Ramadan    







Thank you for reporting!
This image will be automatically disabled when it gets reported by several people.



SANOFI DRUG ADDS TO SURVIVAL IN HEAD, NECK CANCER
Published in Saudi Press Agency on 23 - 10 - 2006

ADDING THE SANOFI-AVENTIS DRUG TAXOTERE TO A TWO-DRUG CHEMOTHERAPY COMBINATION RAISED THE ODDS OF SURVIVING ADVANCED HEAD AND NECK CANCER, U.S. RESEARCHERS SAID ON SUNDAY, ACCORDING TO REUTERS.
A COMPANY-SPONSORED STUDY OF MORE THAN 500 PATIENTS FOUND 62 PERCENT WHO RECEIVED THE TAXOTERE REGIMEN WERE ALIVE AFTER THREE YEARS, COMPARED WITH 48 PERCENT WHO GOT JUST THE TWO-DRUG CHEMOTHERAPY WITHOUT TAXOTERE.
THE LEAD RESEARCHER SAID HE CONSIDERED THE PATIENTS WHO WERE ALIVE AT THAT TIME TO BE CURED OF THE DISEASE BECAUSE MOST RELAPSES OCCUR WITHIN ONE TO TWO YEARS OF TREATMENT.
"IT'S A PRETTY BIG IMPROVEMENT WE'RE TALKING ABOUT, A 30 PERCENT REDUCTION IN MORTALITY," DR. MARSHALL POSNER, DIRECTOR OF HEAD AND NECK ONCOLOGY AT THE DANA-FARBER CANCER INSTITUTE IN BOSTON, TOLD REPORTERS.
THE FINDINGS WERE RELEASED AT AN ANNUAL MEETING OF THE AMERICAN SOCIETY OF CLINICAL ONCOLOGY.
TAXOTERE WAS SANOFI'S THIRD BEST-SELLING DRUG IN 2005 WITH SALES OF $2.07 BILLION (1.609 BILLION EUROS).
ALSO KNOWN BY THE GENERIC NAME DOCETAXEL, TAXOTERE IS APPROVED FOR TREATING BREAST, LUNG AND PROSTATE CANCERS.
DOCTORS CAN USE IT FOR HEAD AND NECK CANCER SINCE IT ALREADY IS ON THE MARKET. SANOFI HAS APPLIED FOR U.S. APPROVAL FOR THAT USE, WHICH WOULD ALLOW PROMOTING IT FOR THAT PURPOSE.
THE TAXOTERE REGIMEN WAS GIVEN AS PART OF AN "INDUCTION" PHASE OVER NINE WEEKS, FOLLOWED BY SEVEN WEEKS OF CHEMOTHERAPY AND RADIATION TO SHRINK TUMORS FURTHER. SOME PATIENTS ALSO HAD SURGERY TO REMOVE REMAINING CANCEROUS TISSUE.
ALMOST 40,000 HEAD AND NECK CANCERS WILL BE DIAGNOSED IN THE UNITED STATES IN 2006, ACCORDING TO AMERICAN CANCER SOCIETY ESTIMATES. ABOUT 7,400 DEATHS FROM THE DISEASE ARE PROJECTED.
THE PATIENTS IN THE STUDY HAD SQUAMOUS CELL CARCINOMAS, WHICH REPRESENT ABOUT 90 PERCENT OF HEAD AND NECK CANCERS. TUMORS WERE LOCATED IN THE LARYNX, THE BACK OF THE THROAT, THE TONGUE, PALATE OR JAW.
THE CHEMOTHERAPY DRUGS USED DURING THE INDUCTION PHASE WERE CISPLATIN AND 5-FLUOROURACIL.
SIDE EFFECTS DURING CHEMOTHERAPY INCLUDED MOUTH SORES, NAUSEA AND VOMITING. RATES WERE SIMILAR AMONG PATIENTS WHO RECEIVED TAXOTERE AND THE OTHERS WHO DID NOT.
RESEARCHERS NOW ARE INTERESTED IN ADDING ANOTHER DRUG SUCH AS IMCLONE SYSTEMS INC.'S AND BRISTOL-MYERS SQUIBB CO.'S ERBITUX TO SEE IF THEY CAN IMPROVE THE TREATMENT, POSNER SAID. ERBITUX IS ONE OF A NUMBER OF NEW TARGETED THERAPIES THAT AIM DIRECTLY AT CANCER CELLS WHILE SPARING HEALTHY CELLS.


Clic here to read the story from its source.