Two U.S. soldiers and an Afghan national were killed and six U.S. military injured Wednesday in separate incidents in southern and eastern Afghanistan, U.S. military said, according to DPA. A U.S. soldier and an Afghan were killed when a coalition vehicle on patrol was struck by a homemade device in Asadabad, the capital of the eastern province of Kunar, U.S. military spokesman Michael Cody told Deutsche Presse-Agentur dpa. "Two U.S. service members were injured. One is receiving medical treatment. The other was treated and released," he added. In a separate incident in the southern province of Kandahar, a U.S. soldier was killed and four injured when their vehicle overturned Wednesday while on patrol. The cause of the accident is being investigated. "Enemy activity was not a factor in the accident," said U.S. military statement in Kabul. "All five service members were evacuated from the scene to Kandahar for treatment. At the Kandahar Airfield Hospital the one service member was pronounced dead, one is being further evacuated for continued treatment and the remaining three were treated and released," the statement added. More than 20,000 U.S.-led troops are presently hunting the remnants of the Taliban regime and their allies in the al-Qaeda network, mainly in the south and southeast.