1990s, researchers found. Declines were greatest in children ages 2 to 18, at 87 percent, the report said. The regional, targeted vaccination approach appears to be a novel one, the report said, but eliminating the disease would require "expansion of existing recommendations to include routine vaccination of all U.S. children." A second study on the subject published in the same journal found that the overall incidence of hepatitis A fell by 95 percent in Israel since free routine vaccination of toddlers began in 1999.