40 ended flat and Zurich's SMI rose 0.2 percent Swiss drugmaker Roche was the biggest positive influence on European markets, gaining 3.5 percent after its majority-owned Genentech unit said its cancer drug Herceptin improved survival of certain breast cancer patients. Among companies reporting, BP closed 0.7 percent higher after reporting a forecast-topping 29 percent rise in its first-quarter profits on the back of high oil prices. Agrochemicals maker Syngenta rose 1.4 percent after first-quarter sales topped forecasts. French software maker Dassault Systemes rose 6.1 percent after reporting quarterly profits that beat expectations and raising its outlook. On the downside, shares in top Nordic telecoms firm TeliaSonera tumbled 6.2 percent on heavy turnover after it reported a surprise fall in first-quarter net profits and warned of earnings pressure for the rest of the year. --More 2252 Local Time 1952 GMT
