Indian biotechnology company Bharat Biotech said on Wednesday it was working on two possible vaccines to fight the Zika virus, which has been linked to birth defects in thousands of babies in Brazil. The virus is spreading rapidly in the Americas, and WHO officials on Tuesday expressed concern that it could hit Africa and Asia as well. No vaccine has been developed so far. One of the possible vaccines is "recombinant", which means it is created by genetic engineering, while the other was "inactivated", and will enter pre-clinical trials in animals in two weeks, Bharat Biotech managing director Krishna Ella told Reuters. An inactivated vaccine is created by killing a pathogen in a way that its ability to replicate is destroyed, but the immune system can still recognise it.