An Asiana Airlines flight packed with more than 300 people slammed onto the runway while landing at San Francisco airport Saturday and caught fire, forcing many to escape by sliding down the emergency inflatable slides and into a trail of metal debris as flames tore through the plane. At least two people who were found outside the wreckage died in the crash, while another 181 people were taken to hospitals, most with minor injuries, authorities said. Five people, including one child, remained in critical condition at San Francisco General Hospital, the region's main trauma center, according to a report of the Associated Press. The investigation has been turned over to the FBI and terrorism has been ruled out, San Francisco Fire Chief Joanne Hayes-White said. Federal aviation and transportation investigators were heading to the scene. Asiana, Boeing and the engine manufacturer, Pratt & Whitney, pledged to work with them. The flight originated in Shanghai, China, and stopped over in Seoul, South Korea, before coming to San Francisco, airport officials said. The airline said there were 16 crew members aboard, and the 291 passengers included 77 South Koreans, 141 Chinese, 61 Americans and one Japanese citizen. The nationalities of the remaining passengers weren't immediately known. Airport spokesman Doug Yakel said 49 people were in serious condition and 132 had less significant injuries. The airport closed for several hours, and when it reopened, two of the four runways were operating. The flight was 10 hours and 23 minutes, according to FlightAware, a flight tracking service.