Cristiano Ronaldo, Gonzalo Higuain and Karim Benzema scored to lead Real Madrid to a 3-0 victory over Espanyol in the Spanish league Tuesday. The Portugal forward had to retake a penalty in the 62nd minute but confidently tucked it into the same spot at the Santiago Bernabeu stadium. With both teams reduced to 10 men, Higuain slid Ronaldo's through ball past Carlos Kameni and inside the near post in the 78th for 2-0. Benzema replaced Higuain and capped a well-worked buildup by Lassana Diarra, as the France striker shook off two Espanyol defenders inside the area before firing past Kameni for the last in the 88th. Madrid took the overnight lead in the standings with Valencia able to regain top spot against Atletico Madrid Wednesday, when Barcelona can also keep pace with a win over Sporting Gijon. Also, Athletic Bilbao continued its good start with a 3-0 victory over Mallorca, while Osasuna picked up its first victory in a 3-1 win over Real Sociedad as a round of midweek games got under way. On Monday Mexico forward Javier Arizmendi's equalizer gave Getafe a 2-2 draw with Deportivo La Coruna in the Spanish league. Arsenal ousts Spurs Samir Nasri scored a pair of extra-time penalty kicks as Arsenal ousted north London rival Tottenham from the League Cup with a 4-1 victory, and Premier League side Everton was beaten in a shootout by third-tier Brentford Tuesday. Tottenham substitute Robbie Keane had canceled out Henri Lansbury's first Arsenal goal to send the game into extra time, but the home side crumbled within 30 seconds of it starting. After being fouled by Sebastien Bassong, Nasri converted from the penalty spot and the France midfielder beat Spurs goalkeeper Stipe Pletikosa again five minutes later when Steven Caulker brought down Marouane Chamakh. Everton, which is yet to win in the Premier League season, went out after Jermaine Beckford and Phil Jagielka missed penalties in a 4-3 shootout loss against Brentford. Bolton was the other Premier League casualty in the third round Tuesday, with Owen Coyle's side losing 1-0 at former club Burnley, which was relegated from the top flight last season. In all-Premier League matches, Stoke beat Fulham 2-0 and West Ham won 2-1 at Sunderland. Elsewhere, Birmingham defeated MK Dons 3-1, Wolverhampton eliminated Notts County 4-2 in extra time, Ipswich won 2-1 at Millwall, Swansea triumphed 3-1 at Peterborough and Leicester beat Portsmouth 2