Venus Williams beat Roberta Vinci 6-1, 6-4 Saturday in the third round of the Sony Ericsson Open, while defending men's champion Andy Murray lost his opening match to American Mardy Fish, 6-4, 6-4. The upset meant Rafael Nadal will overtake Murray for the No. 3 spot in the next rankings. With the win, Fish reached the third round at Key Biscayne for the first time since 2003. Williams, a three-time champion, advanced to the fourth round. Former No. 1 Ana Ivanovic's recent struggles continued with a loss to No. 6 Agnieszka Radwanska, 7-5, 7-5. Advancing on the men's side were No. 5-seeded Robin Soderling and No. 10 Fernando Verdasco. Soderling beat Peter Luczak 7-6 (5), 6-0, and Verdasco eliminated Dudi Sela 6-1, 6-2. Nadal made an efficient start on a rain-soaked day Friday as the fourth seed subdued American Taylor Dent 6-4, 6-3 in his opening match. There was high drama on court for most of the afternoon as Belgium's pocket rocket Olivier Rochus pounded out a 6-2, 6-7 (7-9), 6-4 opening upset over Novak Djokovic to knock the second-seeded Serb out. The victory marked the second win over a top 10 player in Miami for Rochus, who stands just 1.67 meters and ranks 59th in the world. A pair of Americans were bundled out as Frenchman Jeremy Chardy stopped Sam Querrey 4-6, 6-4, 6-2 and Brazil's Tomaz Bellicci added to the misery of veteran James Blake with a 3-6, 6-1, 6-2 defeat. Women's seeds fared better with wins all round. US Open winner Kim Clijsters put last week's early defeat behind her with a 6-1, 6-1 win over Czech Petra Kvitova. Italian number 15 Francesca Schiavone defeated Alize Cornet of France 6-3, 6-2. Former No. 1-ranked Justine Henin, only a handful of tournaments into her comeback from retirement, beat No. 5 Elena Dementieva 6-3, 6