US Secretary of State Hillary Rodham Clinton is kicking off her 2010 diplomacy agenda as she did a year ago, with a trip to Asia meant to strengthen US relations with key partner nations. This time terrorism and the Obama administration's push to improve international cooperation to thwart the threat in Asia and the Pacific, as well as the greater Middle East, will play a prominent role in her talks. Clinton was departing Monday on a 10-day trip scheduled to take her to Australia, New Zealand and Papua New Guinea, with a stop in Hawaii for a policy speech and a one-on-one meeting with her Japanese counterpart. Her fourth trip to Asia since she took office nearly one year ago will highlight the high priority the administration is placing on maintaining strong relations with major allies like Japan and Australia. She also aims to improve ties to other nations seen as like-minded on issues like terrorism, climate change and energy security. In Australia, Clinton is to be joined by Defense Secretary Robert Gates for talks with their foreign affairs and defense counterparts. Among the expected topics: countering the terrorist threat, not only at the flashpoint along the Afghanistan-Pakistan border but across a widening arc that now includes Yemen and Somalia. Clinton makes her first stop in Honolulu. On Tuesday, she is to deliver a speech there at the East-West Center, a research organization founded 50 years ago by Congress to promote relations with Pacific nations. She also is to consult in Honolulu with senior military officials at US Pacific Command, which is responsible for US military relations with countries throughout the Asia-Pacific region. One reason for Clinton's New Zealand visit is to express thanks for its contributions to the war effort in Afghanistan.