Peyton Manning completed every pass early and one big one late, as the Indianapolis Colts stayed unbeaten with a 35-31 win over the Jacksonville Jaguars in the NFL Thursday. Manning threw for 308 yards and four touchdowns, including a 65-yarder to Reggie Wayne to put the Colts ahead for good as they improved to 14-0 for the first time in franchise history. The eventful game included 714 yards, 43 first downs, 10 lead changes, six punts, several big plays and just two turnovers. The Jaguars had a chance to win it with a minute left, but David Garrard overthrew Mike Thomas on a third-and-10 play. Jacob Lacey intercepted the ball, and the Colts ran out the clock. Indianapolis extended its NFL-record winning streak in the regular season to 23 and became the third 14-0 team in league history, joining the 1972 Miami Dolphins and 2007 New England Patriots. New Orleans can join the list with a victory over the Dallas Cowboys Saturday. Jacksonville lost for the third time in the four games and no longer controls its fate in the AFC wild-card race. Manning completed his first 13 passes and finished 23 of 30, picking apart Jacksonville's secondary early and often. Wayne caught five passes for 132 yards. Dallas Clark had seven receptions for 95 yards and two scores. Jaguars quarterback Garrard was 23 of 40 for 223 yards with three touchdowns. Maurice Jones-Drew ran 27 times for 110 yards and a score. But once the Jaguars got behind and abandoned the running game, they had trouble sustaining drives. Pre-game talk that Indianapolis would rest some key players proved inaccurate. Defensive ends Dwight Freeney and Robert Mathis played sparingly, but Manning, Wayne, Clark and the other stars played the entire game. The key moment came with 5:23 remaining, when Manning found Wayne streaking down the sideline for a 65-yard reception. Jaguars safety Reggie Nelson seemed to be fooled by Manning's pump fake, allowing Wayne to get behind the coverage. The first half was a back-and-forth affair that took a little more than an hour to play. Manning was perfect in the first half, completing 12 of 12 passes for 116 yards and had touchdown passes to Clark and Austin Collie. Clark made a sliding grab in the back of the end zone for a 7-3 lead early in the second quarter. Collie's catch, which he briefly bobbled at the goal line, put the Colts ahead 21-17. The Jaguars got within field-goal range just before halftime, but Josh Scobee came up short on a long 57-yard attempt. Jacksonville was also strong in the first half. Garrard completed 12 of 16 passes for 97 yards, and one of his best plays of the season resulted in a touchdown. He faked a handoff, rolled left, then spun around and headed across the field. Tailback Maurice Jones-Drew, who had been blocking, darted toward the end zone and Garrard lofted a perfect pass for the score.