Connecticut held off Missouri 82-75 to stay in the hunt for their third college basketball title, while Villanova upset Pittsburgh 78-76 to reach its first Final Four in 23 years on Saturday. Freshman Kemba Walker scored 23 points as top-seeded Connecticut earned a trip to Detroit as winner of the West Regional. The Huskies will play the Louisville-Michigan State winner in the Final Four. The Huskies blew an early 11-point lead but survived against frenetic third-seeded Missuori, which was denied its first Final Four berth. Connecticut clinched the victory by going 10-for-10 from the line in the final 1:02. The Huskies won their previous national titles in 1999 and 2004. Villanova won the matchup of Big East rivals and advanced to play the winner of the South Regional championship between North Carolina and Oklahoma. Sam Young scored 28 and DeJuan Blair had 20 points and 10 rebounds for Pittsburgh, the first No. 1 seed to lose.