Gavin Floyd held the Detroit Tigers hitless until Edgar Renteria singled with one out in the eighth inning and pitched the Chicago White Sox to a 7-0 victory in the American League on Saturday. Floyd (2-0) had never pitched more than seven innings in the majors. He struck out four and walked four in 7 1-3 innings. Floyd is now 2-0 with a 1.71 ERA in four starts against Detroit since last September. He is 0-3 with a 4.50 ERA in three starts against other teams in that span. Red Sox 4, Yankees 3: At Boston, Manny Ramirez homered and added a two-run double to give Boston the lead, and Josh Beckett rebounded from a bad season debut in a win over New York. Beckett (1-1) allowed just one questionable hit in the first five innings, and five hits in all. He walked one, struck out five and threw two wild pitches in 6 2-3 innings. Mike Mussina (1-2) allowed four runs and eight hits before leaving after Ramirez doubled with two out in the sixth to give Boston a 3-2 lead. Twins 2, Royals 0: At Kansas City, Missouri, Boof Bonser pitched six innings and Jason Kubel homered and scored twice as Minnesota shut out Kansas City for the second straight night. Bonser (1-2) did not give up a hit until Ross Gload singled with one out in the fifth. He allowed three hits, two walks and struck out four. Kubel hit a solo shot off Brett Tomko (1-1) in the third. Orioles 3, Rays 2: At St. Petersburg, Florida, Ramon Hernandez hit a tie-breaking solo homer off Dan Wheeler (0-1) in the ninth inning, after a run-scoring triple, and Baltimore stopped a three-game skid. Carlos Pena homered for the second straight day off Orioles reliever Jamie Walker, a solo shot in the eighth that tied it at 2. Pena has three homers and seven RBIs in the first two games of the three-game series. Athletics 7, Indians 3: At Cleveland, Bobby Crosby hit a three-run homer and Oakland took advantage of 10 walks issued by Cleveland pitchers. Fausto Carmona (1-1) gave up a career-high eight walks in 3 1-3 innings. Crosby's homer capped a four-run seventh off reliever Rafael Perez. Other results: Blue Jays 4, Rangers 1; Mariners 8, Angels 3.Brewers ruin Santana's home debut Milwaukee's Ben Sheets ruined Johan Santana's home debut, outpitching New York's new ace in the Brewers' 5-3 win over the Mets in the National League on Saturday. Three homers helped Milwaukee come from behind and Sheets overcame a shaky start to help Milwaukee end a three-game losing streak. Santana struggled and the Mets' three-game winning streak was snapped. He lasted 6 2-3 innings and allowed five runs. Santana, who allowed 33 home runs with Minnesota last season to lead the league, worked his way out of a number of jams but was hurt by the long ball. Sheets allowed only five hits in 7 2-3 innings. After giving up two runs in the first inning and leaving the bases loaded in the second, he was untouchable, retiring 18 consecutive batters into the eighth inning. Diamondbacks 10, Rockies 3: In Phoenix, Arizona claimed its eighth consecutive victory by downing Colorado. Justin Upton, the first overall pick in the 2005 draft, went 3-for-3 with four RBIs, including a three-run homer. Arizona improved to 5-0 against Colorado this season and is already 3-1/2 games clear top of the West division. Other results: Cardinals 8, Giants 7, 10 innings; Braves 10, Nationals 2; Phillies 7, Cubs 1; Pirates 4, Reds 3; Astros 5, Marlins 0; Dodgers 11, Padres 1. __