NEW YORK — Ana Ivanovic of Serbia and Kei Nishikori of Japan recorded straight set victories to make the second round of the US Open Tuesday. The eighth-seeded Serb beat American Alison Riske 6-3, 6-0, while tenth-seeded Nishikori cruised to a 6-2, 6-4, 6-2 victory over American Wayne Odesnik, showing no apparent effects from a toe injury that hampered his preparations. Ivanovic has won 48 matches this year, more than anyone else on tour. The 24-year-old Riske made a breakthrough at last year's US Open, reaching the fourth round after an upset of Petra Kvitova. She reached a career-high ranking of No. 40 this summer. Nishikori needed more than two hours to dispatch the 176th-ranked Odesnik, a grinding baseliner who earned a wild card, his first appearance in five years, after serving a yearlong ban for getting caught with human growth hormone. Former champions Novak Djokovic and Maria Sharapova sparkled under the Arthur Ashe Stadium lights to end a steamy first day that proved more than a little stressful for several of the favorites Monday. Djokovic, who had won only two matches in the hard court run-up to the season's final Grand Slam after getting married just days after his Wimbledon triumph, was back to his best once the center court spotlight shone on him at Flushing Meadows. The 2011 champion treated his first-round match against unseeded 22-year-old Argentine Diego Schwartzman like a breezy workout, dominating in all phases with 24 winners including seven aces in a 6-1, 6-2, 6-4 rout. His fast work followed a scintillating finish by French Open champion and 2006 winner Sharapova, as the fifth seed won 10 straight games to prevail 6-4, 6-0 after falling 2-4 behind against her Russian compatriot and old friend Maria Kirilenko. Despite the night program starting one hour later than scheduled due to ceremonies featuring bands, speeches and fireworks, Djokovic enabled the New York night crowd to head to the exits shortly before the stroke of midnight. “I'm very pleased,” the Serbian world No. 1 said in a courtside interview after his 97-minute win. “It's never easy to start a US Open smoothly.” Several of the favorites at Flushing Meadows could attest to his opinion. Busy bees made life difficult for two grizzled veterans and a pair of favorites were forced to work overtime on a hot, steamy day at the US National Tennis Center that drew a combined 57,000 fans to the day and night sessions. Eighth-seeded 2012 champion Andy Murray fought off cramps to beat Dutchman Robin Haase in four painful sets, while women's second seed Simona Halep lost an early tiebreak to US debutant Danielle Collins before claiming victory. And in an intriguing match-up of 19th seed Venus Williams and Kimiko Date-Krumm of Japan, the oldest players in the women's draw, some pesky bees joined in and refused to leave them alone. Murray appeared on course for an easy victory before he fell victim to cramps that left him stretching and straining to get comfortable before clinching a 6-3, 7-6 (6), 1-6, 7-5 victory over Haase. “I felt extremely good before the match, and I did train very, very hard to get ready for the tournament,” said Murray. Murray said he might consult with a nutritionist before meeting his second-round opponent, Germany's Matthias Bachinger. A less serious intrusion hit the irresistible women's clash between seven-times grand slam singles winner Williams and Japan's remarkable Date-Krumm, who were beset by bees. First the 43-year-old Japanese player and later 34-year-old Williams dipped, ducked and danced away before ballgirls helped usher the stubborn swarm away from the baseline. When finally left to play tennis on a sun-bathed Arthur Ashe Stadium court, Williams stung her opponent 2-6, 6-3, 6-3 to advance. In an upset on the men's side, twice US Open semifinalist Mikhail Youzhny of Russia, the 21st seed, fell to big-serving Australian teenager Nick Kyrgios 7-5, 7-6 (4), 2-6, 7-6 (1). The 19-year-old Kyrgios, who made a Wimbledon splash by ousting Rafa Nadal in the fourth round to reach the quarterfinals, blasted 26 aces. The 60th-ranked Kyrgios moved on to a second-round match against Italy's Andreas Seppi. Advancing with relative ease in straight sets were Australian Open champion Stan Wawrinka of Switzerland and fifth-seeded Canadian Milos Raonic, a Wimbledon semifinalist. The Swiss third seed beat Jiri Vesely of the Czech Republic to set up a second-round test against Brazilian Thomaz Bellucci, while big-serving Raonic defeated Japan's Taro Daniel to get to the next round against Peter Gojowczyk of Germany. Halep survived a scare in the tournament's first match on stadium court before overtaking Collins 6-7 (2) 6-1 6-2. She moves on to face Slovakian Jana Cepelova, a 2-6, 7-5, 6-1 winner over Spain's Maria-Teresa Torro-Flor, in the second round of the season's last Grand Slam. Also advancing on the women's side were fourth seed Agnieszka Radwanska of Poland, sixth seed Angelique Kerber of Germany, and Jelena Jankovic of Serbia, the ninth seed. — Agencies