Juventus regained the Serie A lead after Alessandro Del Piero scored a late free kick on his 700th appearance for the club to seal a 2-1 home win over Lazio Wednesday. AC Milan had beaten Chievo 1-0 Tuesday to throw down the gauntlet to its rival but Juve went a point clear after a hard-fought game where Lazio's Stefano Mauri had equalized Simone Pepe's opener. Six games remain in one of the closest title run-ins in Italy for many years while the defeat for third-placed Lazio opened up the battle for the Champions League qualifying berth. AS Roma beat fourth-placed Udinese 3-1 to go four points behind Lazio, while Napoli lost 3-1 at home to Atalanta and Inter Milan beat Siena 2-1 thanks to Diego Milito's San Siro double. Inter is now level with Napoli in a potential final Europa League spot as new coach Andrea Stramaccioni won for the second time in his three games in charge and Napoli failed to win for the fifth straight time in the league. In other results, bottom side Cesena is almost down after a 1-1 draw at Genoa, second-bottom Novara also look doomed following a 2-0 loss at Parma. Lecce, which occupies the other relegation place, boosted its hopes of survival and cut the gap to Genoa to two points with a 2-1 victory at fading Catania. Dortmund goes clear In Berlin, Bayern Munich winger Arjen Robben missed a late penalty as defending champion Borussia Dortmund staked a massive claim on the Bundesliga title with a 1-0 win over its main rival Wednesday. Robert Lewandowski struck his 20th goal of the season in the 77th minute to leave Dortmund six points clear of Bayern with four games remaining. Third-place Schalke was unable to take advantage of Bayern's loss by slumping to a 4-1 defeat at Nuremberg, Hoffenheim routed Hamburger SV 4-0, Hannover beat Wolfsburg 2-0 in a battle to qualify for Europe, and bottom side Kaiserslautern is almost certainly relegated after losing 3-1 at Bayer Leverkusen. More than 450,000 fans applied for tickets for Dortmund's likely title decider with Bayern, which had been billed by German media as “the game of games.” “If Dortmund win they'll be champions. If Bayern win they'll have it their hands to become champions,” said former Bayern great Franz Beckenbauer — before tipping a 2-2 draw.