Jose Ramirez was 4 for 4 with a pair of three-run homers for Cleveland, and Detroit Tigers ace Justin Verlander matched a career high by allowing nine runs Saturday in a 13-6 loss to the Indians. Ramirez had a career-high six RBIs with home runs in the first off Verlander (1-1) and in the eighth against Anibal Sanchez. Verlander (1-1) gave up 11 hits in four-plus innings, including home runs by Carlos Santana and Lonnie Chisenhall. Santana had three of Cleveland's 19 hits and four RBIs, Corey Kluber (1-1) struck out eight in 6 1/3 innings, allowing six runs and eight hits. Mariners 5, Rangers 0: James Paxton extended his season-opening scoreless streak to 21 innings and Taylor Motter hit a three-run homer as Seattle beat Texas. Paxton (2-0) threw eight innings of two-hit ball, walking one and striking out nine. He hasn't allowed a run yet in three starts this year, and his scoreless stretch is a team record to open a season. Andrew Cashner (0-1) lost in his first start since signing with Texas as a free agent. Twins 6, White Sox 0: Ervin Santana (3-0) pitched a one-hitter for the first complete-game victory by a pitcher in MLB this season, stopping Chicago's three-game winning streak. Santana's (3-0) struck out eight, walked one and retired his final 18 batters. Chicago had just two runners: Omar Narvaez singled with one out in the third and Avisail Garcia walked leading off the fourth. Jose Quintana (0-3) gave up hits to six of his first seven batters in a 39-pitch first inning, including Max Kepler's two-run triple. Rockies 5, Giants 0: Tyler Chatwood (1-2) pitched 5 2/3 perfect innings before Chris Marrero's single and finished with a two-hitter for his first MLB shutout in Colorado's win over San Francisco. Nolan Arenado had three hits, including a home run off Matt Moore (1-2), who allowed five runs, 10 hits and three walks in 5 2/3 innings. Dodgers 8, Diamondbacks 4: Yasiel Puig hit a three-run homer in the eighth inning and Los Angeles overcame a sloppy defensive game to beat Arizona. Alex Wood (1-0) pitched 3 1/3 scoreless innings of relief to earn the win and Kenley Jansen got the last four outs for his third save. Diamondbacks starter Patrick Corbin (1-2) struggled in his six innings, giving up five runs — three earned — and nine hits with three walks. Yankees 3, Cardinals 2: St. Louis ace Carlos Martinez (0-2) put on a historically uneven performance, walking a career-high eight while striking out 11 in 5 1/3 innings in the Cardinals' loss to New York. Martinez was the first pitcher since Randy Johnson in 1993 with at least eight walks and 11 strikeouts in a game. The Yankees won their sixth straight despite tying a team record by fanning 17 times. They got plenty of help from sloppy St. Louis, which at 3-8 is off to its worst start in 20 years and has the poorest record in the National League. CC Sabathia (2-0) took a shutout into the eighth. Blue Jays 2, Orioles 1: Kendrys Morales homered off Tyler Wilson (1-1) leading off the bottom of the ninth, and Toronto (2-9) stopped a seven-game losing streak. Roberto Osuna (1-0) had allowed Jonathan Schoop's sacrifice fly in the top half. Reds 7, Brewers 5: Jesse Winker doubled home the go-ahead run in the sixth off Carlos Torres (0-1) with his first MLB hit, and Cincinnati overcame two more homers by Eric Thames and stopped Milwaukee's four-game winning streak. Pirates 8, Cubs 7: Andrew McCutchen hit a go-ahead, three-run homer of Pedro Strop (0-1) in a five-run seventh as Pittsburgh topped Chicago. Red Sox 2, Rays 1: Chris Sale (1-1) struck out 12 over seven innings for his first victory with Boston, allowing one run and three hits. Astros 10, Athletics 6: George Springer hit a two-run homer in the eighth as Houston rallied from a 5-0 deficit. Phillies 4, Nationals 2: Cesar Hernandez hit a tiebreaking, two-run homer off Joe Blanton (0-2) in the eighth to lead Philadelphia past Washington. Other results: Marlins 5, Mets 4; Braves 4, Padres 2; Royals 3, Angels 2. — AP