World No. 1 and three-time defending champion Serena Williams and second-ranked Andy Murray both crashed out of the ATP and WTA Miami Open on a Monday filled with upsets. [caption id="attachment_45045" align="alignright" width="300"] Grigor Dimitrov celebrates after his match against Andy Murray during the Miami Open in Key Biscayne, Florida, Monday. — Reuters[/caption] Russian 15th seed Svetlana Kuznetsova stunned 21-time Grand Slam champion Serena 6-7 (3-7), 6-1, 6-2, while British world No. 2 Murray dropped a third-round match to Bulgarian 26th seed Grigor Dimitrov 6-7 (1-7), 6-4, 6-3. Serena and Murray each made 55 unforced errors, fading in the third set when it mattered most. "A lot of unforced errors crept in and he was a lot more solid than me," said Murray, who had 22 unforced errors in the last set alone. "I made many more mistakes than usual, especially in the third set." Serena's struggles prompted questions about her fitness and movement, irking the 21-time Grand Slam champion. "I don't think it's appropriate to criticize my movement right now," Serena said. "I did the best I could. I can't win every match. These players come out and give their best. I have to give 300 percent every match." The 34-year-old American was seeking her ninth Miami crown but instead matched her earliest-ever exit from 2000 with a fourth-round departure. "It's obviously disappointing, but I have won here a lot, so it's OK," Serena said. Also ousted were world No. 2 Agnieszka Radwanska of Poland, eliminated by 20th-ranked Swiss Timea Bacsinszky 2-6, 6-4, 6-2, and Spanish fourth seed Garbine Muguruza, who fell 7-6 (8-6), 7-6 (7-4) to 13th seed Victoria Azarenka of Belarus. Only two of the top 12 seeds — No. 2 Angelique Kerber and No. 5 Simona Halep — remain on the women's side. Top-ranked Novak Djokovic is the last top-five man remaining and only three of the men's top eight made the last 16. Two-time Grand Slam champion Murray failed in his bid for a third Miami trophy and fourth final in five seasons. The 28-year-old Scotsman dominated the tie-breaker but fell behind 4-0 in the second set and stumbled after leading 3-1 in the third, swatting a forehand long on match point to fall after two hours and 24 minutes. "It's the best result of the year for me," Dimitrov said. "I just played better in the good moments. That was it." Serena, who said she was physically fine and not affected by the heat and humidity, arrived having lost back-to-back finals for the first time since 2004, falling to Germany's Angelique Kerber at the Australian Open and Azarenka at Indian Wells. "She struggled a little bit losing the final of the Australian Open, but she is still No. 1 in the world," Kuznetsova said. "I don't see much to be depressed about." Kuznetsova, seeded 15th, next faces 30th-seeded compatriot Ekaterina Makarova, who ousted Ukraine's 12th-seeded Elina Svitolina 6-1, 6-4 Radwanska, the 2012 Miami champion, faded in the second set as well to Bacsinszky, a 2015 French Open semifinalist. Bacsinszky's quarterfinal foe will be Romania's Halep, who eliminated 69th-ranked British wildcard Heather Watson 6-3, 6-4. Next up for Azarenka is British 24th seed Johanna Konta. And Australian Open champion Kerber of Germany will face US 22nd seed Madison Keys after dispatching Hungary's Timea Babos 6-2, 3-6, 6-4. Japanese sixth seed Kei Nishikori cruised into the fourth round by routing Ukraine's 27th-seeded Alexandr Dolgopolov 6-2, 6-2. Nishikori, the top-ranked player remaining in his half of the draw, was to play Tuesday for a quarterfinal berth against Spanish 17th seed Roberto Bautista Agut.
