Diabetes mellitus (diabetes) is a chronic disease caused by inherited and/or acquired deficiency in production of insulin by the pancreas, or by the ineffectiveness of the insulin produced. It is characterized by abnormally high concentrations of glucose in the blood. The WHO criterion for diagnosis of diabetes mellitus is a level of fasting plasma glucose of 7.0 mmol/L (1,26 g/L)4 Diabetes treatments are aimed at lowering glucose levels in the blood, in order to delay the appearance of complications. Insulins are given as a substitute (Type 1) or a supplement (Type 2) to natural insulin secretion. __