Hundreds of people sickened in the outbreak have developed hemolytic uremic syndrome, or HUS, a life-threatening complication of E. coli infections. The syndrome, which results in the destruction of red blood cells and severe kidney problems, usually arises about a week after diarrhea starts. Symptoms of HUS include decreased frequency of urination, extreme fatigue and the loss of the skin's pink color. Children, the elderly and people with compromised immune systems usually are at highest risk for HUS.
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