Syria neighbors are following carefully what is happening there. Each of them is visualizing the situation thereafter regarding security and policy because the location of this country becomes the basis of all variables during half century of post-colonization. Israel is worried because the happenings that passed from Egypt to Syria may change the old policies and wage a new war or start an incomplete peace at least. Israel thinks that the new unknown possibilities in both countries will not lead to governments that accept a truce without a price or keeping the situation calm as before. Recently, Turkey went through good relations with Syria by raising the economical and political deals to the extent of opening the boundaries to create semi-integration between both countries. However, the situation changed and Turkey started to condemn the use of arms against Syrian people when Erdogan publicly condemned these actions because, as he said, what he saw is more than imagined. Practically, Turkey chose the side of people against government which is a normal attitude in front of a condemned government. Iran and Iraq agreed to support the current government because of their similar ideologies and the fears of new rules that will change the current alliance. Iraq fears of a Sunni government which would be a branch of the Sunnis in Iraq. As for Iran, fears are much bigger and farsighted because the change in Syria will make the dream of Shiite arch in which Syria played a great role by supplying Hezbollah by arms, money and even the security coordination including the exchange of information and the coordination regarding the Palestinian issue. Lebanon, as usual, is divided between supporting and opposing parties according to their advantage. However, the majority of them welcome the change that may restore balance between the Lebanese parties and release the guardianship of Syria and its supporters. Jordan has nothing to do but silence according to the proverb that says ‘...silence is gold'; however, any change in the Syrian track will nullify this silence especially if Syrian refugees head to it and of course increase its economical and social burdens. The Syrian pressure comes from inside as the cost of mobilizing army and their dispersal all over Syria including the maintenance, fuel and spare parts. Also, the paralyzing of society who lost the trade exchange with other countries that affected the tourism too. This economy weakness will press the exert pressure on the government which is losing its reserves and resources that lead to failure of providing the basic needs of people during the crisis. As for security, some persons will cross to the Syrian boundaries form all sides, i.e. arms and money smuggling will increase. Then some exterior elements, whether with or against government, will appear to fuel the conflict which unstable Syria will suffer from.